Checklist: These 9 steps will future-proof your hospital’s precision medicine program


1. Precision medical treatment is not hype, not fashion.

“I believe the commitment of precision medical care is true,” said John Halamka, chief information officer of the BIS Israeli deacon medical center in Boston. He predicts that we will “in five years, but in one year”.

“I think we are approaching the critical quality in the sense of precision medicine, and realize that it will become part of the nursing standard,” said Don Ruud, chief executive of translation software company (Don Rule).

2. Make reasonable data management strategies.

“In terms of IT, there is a well-designed ontology to collect patient information and be able to gain insight in a period of time,” said Don Khloe, chief executive of translation software company (Don Rule).

“Whether they are community hospitals or academic medical centers, they now have a basic data problem,” adds Joel Diamond, 2b’s chief medical officer, Joel Diamond. Start to figure out where the data source is. Find laboratories for oncologists who are conducting genetic tests, living tissue tests, and physical examination results. Now, liquid biopsies are becoming more and more prominent, and there are many laboratories doing it.

3. Consider the availability of data.

“If it was stored in a system and not elsewhere, we would be ashamed,” Diamond said. “We can’t live in a world of paper only, you can’t do anything with it.”

4. Prepare for new investment in the IT infrastructure.

“Health system needs to understand the cost and complexity of supporting infrastructure for large-scale clinical trials and registration,” said Sean Ope, chief scientific officer of Vantari Genetics (Shaun Opie).

5. Let doctors and clinicians receive education.

“If a drug has a 30% probability of being overmetabolizing, rather than being used by a specific patient, we should know this and consider this when we prescribe drugs.” This is very simple, not difficult, we should build it on the basis of continuing medical education.

I read my magazine American family doctor and the CME I got from those articles, and I rarely see articles about genomics and precision medicine. “We can start here. We can educate people about American Medical Genetics and genomics.

6. Provide the right information and tools for the patient.

The rise of consumer – centric genetic tests like 23andMe is changing the way patients communicate with doctors. He said: “these tests can show a series of genetic predisposition to diseases, and put forward a series of potential medical problems, but not all of them are feasible.” Banner Alzheimer’s Institute chief scientist Jessica Langbaum said, as more and more people accept direct to consumer testing, doctors will be asked to help them explain these results. “They may not really understand what the report tells them, and do not know what it means to their biological relatives.”

7. This is not just genomics: social determinants play a role.

“The meaning of precision medical treatment is not only about genes and drugs,” said Vik Bakhru, the chief operating officer of the Spanish speaking patients participating in the platform. He said that 70% of a person’s health is determined by socioeconomic or environmental factors. However, although EHRs is almost everywhere, key information is still not often recorded to help guide the care and treatment plans.

8. There is a reasonable concern for understanding the participants.

“The current situation is that 80% of the research fails to meet their recruitment goals and timetables, because it is difficult to find qualified participants,” Baum said. “At the national level, we need to solve some of the major problems. We often hear that people are willing to take part in a study, but they are afraid to do it because they can’t risk losing health insurance.

9. The potential rewards are huge, but there’s a lot of hard work to do.

“Most patients yearn for more effective treatment, and when the problem sets are well defined, technical problems are easy to solve,” Rule said. “The main problem today is that the supplier’s gap is limited due to the lack of evidence for successful suppliers and the lack of successful evidence, because the utilization rate is low.”


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